An Introduction to Industrial Toxicology with Examples of Interest from the GaAs, InP, and GaN Technology

Proust*, Nicole; Picot, André
(TRT-Fr,Orsay and CNRS, Gif sur Yvette, FRANCE)

AN INTRODUCTION TO INDUSTRIAL TOXICOLOGY FOLLOWED BY SOME EXAMPLES OF INTEREST FROM THE GaAs,InP AND GaN TECHNOLOGY. PROUST Nicole* (TRT-Fr and CNRS) and PICOT André (CNRS). This course on industrial toxicology is dedicated to several target audiences (safety, industrial hygiene, medical, environmental). A basic knowledge on industrial toxicology is very important and useful when you have to deal with toxic hazards related to chemicals in use at work or when you have to practice biological monitoring after a possible exposure to toxicants. This one day course is in two parts. In the 1rst one there is an introduction to industrial toxicology: key word definition, ways of penetration, absorption, distribution, biotransformation of toxicants [Phase I and Phase II possible chemical reactions which objectives are the transformation of the initial toxicant into water soluble metabolites], excretion and biometrology, target organ toxicity, major toxic effects. In the 2nd part there are practical examples. Toxicity and biometrology of arsenic compounds are discussed. An important study has been conducted in our center to survey the workers, results on biometrology are presented. For an accurate hazard evaluation, it is necessary to take speciation into account. Toxicity of metals such as gallium and indium currently in use is reported. Some hazards related to GaAs, InP and GaN epitaxial growth [MOCVD and MBE) are discussed. Our analytical approach and the results of our research work are presented. This research work has been supported by the French Administration and the European Commission. (This is a part of “Toxicology and Safety in Microelectronics”, a course awarded in Europe, the 1rst price “Experts in Health and Safety at Work”)

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